- 产品编号
- bsm-30095M-FITC
- 产品分类
- 抗体 / 标记一抗 / FITC
- 英文名称
- human CD45/FITC
- 中文名称
- FITC标记的小鼠抗人CD45单克隆抗体
- 英文别名
-
B220; CD 45; CD-45; cd45 antigen; ec3.1.3.48; CD45R; GP180; GP180; GP 180; L CA; LCA; L-CA; Leukocyte common antigen; LY5; Ly-5 glycoprotein; Protein tyrosine phosphatase receptor type C; Protein tyrosine phosphatase receptor type c polypeptide; protein tyrosine phosphatase, receptor type, C; Receptor-type tyrosine-protein phosphatase C; PTPRC; PTPRC_HUMAN; SCID due to PTPRC deficiency; T200; T200 glycoprotein; T200 leukocyte common antigen; Human homolog of severe combined immunodeficiency due to PTPRC deficiency.
- 交叉反应
- (predicted: Rat, Mouse, Human)
- 标记
- FITC
- 抗体来源
- Mouse
- 抗体类型
- Monoclonal
- 克隆号
- HI30
- 免疫原
- Recombinant human CD45
- 纯化方法
- Affinity purified by Protein G
- 性状
- Liquid
- 浓度
- 1mg/ml
- 储存液
- 0.01M TBS(pH=7.4)
- 保存条件
- Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
- PubMed
- PubMed
- 背景资料
- CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, naïve T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naïve to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1.
- GeneID
- 5788
- Swiss
- P08575
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
scatter diagram showing peripheral blood lymphocytes stained with bsm-30095M-FITC. The cells were incubated with the antibody (bsm-30095M-FITC, 5 µl/Test) for 30 min at 22°C. Acquisition of >10,000 events was performed.
