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human CD19/FITC (bsm-30096M-FITC)
  • datasheet
  • 概述
    产品编号
    bsm-30096M-FITC
    产品分类
    抗体 / 标记一抗 / FITC
    英文名称
    human CD19/FITC
    中文名称
    FITC标记的小鼠抗人CD19单克隆抗体
    英文别名
    CD19_HUMAN; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12; CD_antigen: CD19; B-lymphocyte surface antigen B4; Leu 12; Leu12;

     

    交叉反应
    (predicted: Rat, Mouse, Human)
    标记
    FITC

     

    抗体来源
    Mouse
    抗体类型
    Monoclonal
    克隆号
    HI19a
    免疫原
    KLH conjugated synthetic peptide derived from human CD19
    纯化方法
    Affinity purified by Protein G
    亚型
    Mouse IgG1
    性状
    Liquid
    浓度
    1mg/ml
    储存液
    0.01M TBS(pH=7.4)
    保存条件
    Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    PubMed
    PubMed

     

    背景资料
    This gene encodes a member of the immunoglobulin gene superfamily. Expression of this cell surface protein is restricted to B cell lymphocytes. This protein is a reliable marker for pre-B cells but its expression diminishes during terminal B cell differentiation in antibody secreting plasma cells. The protein has two N-terminal extracellular Ig-like domains separated by a non-Ig-like domain, a hydrophobic transmembrane domain, and a large C-terminal cytoplasmic domain. This protein forms a complex with several membrane proteins including complement receptor type 2 (CD21) and tetraspanin (CD81) and this complex reduces the threshold for antigen-initiated B cell activation. Activation of this B-cell antigen receptor complex activates the phosphatidylinositol 3-kinase signalling pathway and the subsequent release of intracellular stores of calcium ions. This protein is a target of chimeric antigen receptor (CAR) T-cells used in the treatment of lymphoblastic leukemia. Mutations in this gene are associated with the disease common variable immunodeficiency 3 (CVID3) which results in a failure of B-cell differentiation and impaired secretion of immunoglobulins. CVID3 is characterized by hypogammaglobulinemia, an inability to mount an antibody response to antigen, and recurrent bacterial infections. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2020]

     

    GeneID
    12478
    Swiss
    P25918
    Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
  • 相关标记抗体
    产品名称 产品编号 规格 价格
    human CD19/APC bsm-30096M-APC 2980.00
    human CD19/APC-Cy5 bsm-30096M-APC-Cy5 2980.00
    human CD19/APC-Cy5.5 bsm-30096M-APC-Cy5.5 2980.00
    human CD19/APC-Cy7 bsm-30096M-APC-Cy7 2980.00
    human CD19/Cy3 bsm-30096M-Cy3 2980.00
    human CD19/Cy5 bsm-30096M-Cy5 2980.00
    human CD19/Cy5.5 bsm-30096M-Cy5.5 2980.00
    human CD19/Cy7 bsm-30096M-Cy7 2980.00
    human CD19/FITC bsm-30096M-FITC 2980.00
    human CD19/RBITC bsm-30096M-RBITC 2980.00
    human CD19/PerCP bsm-30096M-PerCP 2980.00
    human CD19/PerCP-Cy5.5 bsm-30096M-PerCP-Cy5.5 2980.00
    human CD19/PerCP-Cy7 bsm-30096M-PerCP-Cy7 2980.00
    human CD19/PE bsm-30096M-PE 2980.00
    human CD19/PE-Cy3 bsm-30096M-PE-Cy3 2980.00
    human CD19/PE-Cy5 bsm-30096M-PE-Cy5 2980.00
    human CD19/PE-Cy5.5 bsm-30096M-PE-Cy5.5 2980.00
    human CD19/PE-Cy7 bsm-30096M-PE-Cy7 2980.00
    human CD19/BF350 bsm-30096M-BF350 2980.00
    human CD19/BF405 bsm-30096M-BF405 2980.00
    human CD19/BF488 bsm-30096M-BF488 2980.00
    human CD19/BF555 bsm-30096M-BF555 2980.00
    human CD19/BF594 bsm-30096M-BF594 2980.00
    human CD19/BF647 bsm-30096M-BF647 2980.00
    human CD19/BF680 bsm-30096M-BF680 2980.00
    human CD19/BF750 bsm-30096M-BF750 2980.00
  • 应用
    我们在涵盖以下测试应用中使用 bsm-30096M-FITC
    应用笔记包括推荐的起始稀释液; 最佳稀释度/浓度应由最终用户确定。
    应用 评级 推荐稀释比例
    Flow-Cyt .
  • 图片资料
    1. scatter diagram showing peripheral blood lymphocytes stained with bsm-30096M-FITC. The cells were incubated with the antibody (bsm-30096M-FITC, 5 µl/Test) for 30 min at 22°C. Acquisition of >10,000 events was performed.
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2980.00bsm-30096M-FITC-100ul
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