GCP4 Rabbit pAb (一抗) | Bioss

bs-13320R

宠物抗体、农牧业/家禽抗体

GCP4 Rabbit pAb

γ-微管蛋白GCP4抗体

76P; GCP-4; GCP4; Grip76; MCCRP3; 4932441P04Rik; D2Ertd435e; GCP4_HUMAN; TUBGCP4; hGCP4; Gamma-ring complex protein 76 kDa (h76p | hGrip76); GCP4_MOUSE; tubulin gamma complex component 4; tubulin, gamma complex associated protein 4; tubulin gamma complex associated protein 4; gamma-tubulin complex protein 4; gamma-ring complex protein 76 kDa

Rabbit

KLH conjugated synthetic peptide derived from human GCP4: 101-200/667

Liquid

affinity purified by Protein A

Polyclonal

76 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complex-associated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP4 (gamma-tubulin complex component 4), also known as TUBGCP4, is a ubiquitously expressed 667 amino acid member of the gamma-Tubulin complex that localizes to the metaphase spindle during mitosis. In response to proteosome inhibition, GCP4 exhibits increased accumulation at the pericentiolar material where it participates in microtubule organization and nucleation.